Transcranial sonography findings in welding‐related Parkinsonism in comparison to Parkinson's disease
Identifieur interne : 002561 ( Main/Exploration ); précédent : 002560; suivant : 002562Transcranial sonography findings in welding‐related Parkinsonism in comparison to Parkinson's disease
Auteurs : Uwe Walter [Allemagne] ; Dirk Dressler [Allemagne] ; Christian Lindemann [Chili] ; Andrea Slachevsky [Chili] ; Marcelo Miranda [Chili]Source :
- Movement Disorders [ 0885-3185 ] ; 2008-01.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
- Adult, Comparative study, Diagnosis, Differential, Dopamine Agonists (therapeutic use), Drug Resistance, Echoencephalography (instrumentation), Encephalon, Humans, Levodopa (therapeutic use), Locus niger, Male, Nervous system diseases, Occupational Diseases (diagnosis), Occupational Diseases (etiology), Parkinson Disease (diagnosis), Parkinson Disease (drug therapy), Parkinson disease, Parkinson's disease, Parkinsonian Disorders (diagnosis), Parkinsonian Disorders (drug therapy), Parkinsonian Disorders (etiology), Parkinsonism, Sonography, Substantia Nigra (ultrasonography), Ultrasonography, Doppler, Transcranial (methods), Welding, brain parenchyma sonography, substantia nigra, transcranial sonography, welding‐related Parkinsonism.
- MESH :
- chemical , therapeutic use : Dopamine Agonists, Levodopa.
- diagnosis : Occupational Diseases, Parkinson Disease, Parkinsonian Disorders.
- drug therapy : Parkinson Disease, Parkinsonian Disorders.
- etiology : Occupational Diseases, Parkinsonian Disorders.
- instrumentation : Echoencephalography.
- methods : Ultrasonography, Doppler, Transcranial.
- ultrasonography : Substantia Nigra.
- Adult, Diagnosis, Differential, Drug Resistance, Humans, Male, Welding.
Abstract
The pathogenetic relationship of welding‐related Parkinsonism (WP) and idiopathic Parkinson's disease (PD) is a matter of debate. In the present study, we compared transcranial sonography (TCS) findings in patients with WP and PD. Two male patients with WP, who had developed levodopa‐resistant akinetic‐rigid Parkinsonism without ongoing progression after having worked as welders for many years in Chilean mines in confined spaces without adequate ventilation, and three age‐matched male patients with clinically definite akinetic‐rigid PD were studied with TCS in a random order by two investigators blind to clinical diagnoses. In both WP patients, normal echogenicity of substantia nigra was found whereas all PD patients exhibited marked substantia nigra hyperechogenicity, previously reported as a characteristic TCS finding in idiopathic PD. In contrast, lenticular nucleus was hyperechogenic in both WP patients but only in one of the PD patients. TCS findings suggest a different pathophysiology of Parkinsonism in WP and PD patients. © 2007 Movement Disorder Society
Url:
DOI: 10.1002/mds.21795
Affiliations:
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Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2008-01">2008-01</date><biblScope unit="vol">23</biblScope><biblScope unit="issue">1</biblScope><biblScope unit="page" from="141">141</biblScope><biblScope unit="page" to="145">145</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">0A2CEE0ADDA7752DA65CE00241DEAD83D9B0337F</idno><idno type="DOI">10.1002/mds.21795</idno><idno type="ArticleID">MDS21795</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Comparative study</term><term>Diagnosis, Differential</term><term>Dopamine Agonists (therapeutic use)</term><term>Drug Resistance</term><term>Echoencephalography (instrumentation)</term><term>Encephalon</term><term>Humans</term><term>Levodopa (therapeutic use)</term><term>Locus niger</term><term>Male</term><term>Nervous system diseases</term><term>Occupational Diseases (diagnosis)</term><term>Occupational Diseases (etiology)</term><term>Parkinson Disease (diagnosis)</term><term>Parkinson Disease (drug therapy)</term><term>Parkinson disease</term><term>Parkinson's disease</term><term>Parkinsonian Disorders (diagnosis)</term><term>Parkinsonian Disorders (drug therapy)</term><term>Parkinsonian Disorders (etiology)</term><term>Parkinsonism</term><term>Sonography</term><term>Substantia Nigra (ultrasonography)</term><term>Ultrasonography, Doppler, Transcranial (methods)</term><term>Welding</term><term>brain parenchyma sonography</term><term>substantia nigra</term><term>transcranial sonography</term><term>welding‐related Parkinsonism</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Dopamine Agonists</term><term>Levodopa</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Occupational Diseases</term><term>Parkinson Disease</term><term>Parkinsonian Disorders</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Parkinson Disease</term><term>Parkinsonian Disorders</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Occupational Diseases</term><term>Parkinsonian Disorders</term></keywords><keywords scheme="MESH" qualifier="instrumentation" xml:lang="en"><term>Echoencephalography</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Ultrasonography, Doppler, Transcranial</term></keywords><keywords scheme="MESH" qualifier="ultrasonography" xml:lang="en"><term>Substantia Nigra</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Diagnosis, Differential</term><term>Drug Resistance</term><term>Humans</term><term>Male</term><term>Welding</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Encéphale</term><term>Etude comparative</term><term>Exploration ultrason</term><term>Locus niger</term><term>Maladie de Parkinson</term><term>Parkinsonisme</term><term>Pathologie du système nerveux</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The pathogenetic relationship of welding‐related Parkinsonism (WP) and idiopathic Parkinson's disease (PD) is a matter of debate. In the present study, we compared transcranial sonography (TCS) findings in patients with WP and PD. Two male patients with WP, who had developed levodopa‐resistant akinetic‐rigid Parkinsonism without ongoing progression after having worked as welders for many years in Chilean mines in confined spaces without adequate ventilation, and three age‐matched male patients with clinically definite akinetic‐rigid PD were studied with TCS in a random order by two investigators blind to clinical diagnoses. In both WP patients, normal echogenicity of substantia nigra was found whereas all PD patients exhibited marked substantia nigra hyperechogenicity, previously reported as a characteristic TCS finding in idiopathic PD. In contrast, lenticular nucleus was hyperechogenic in both WP patients but only in one of the PD patients. TCS findings suggest a different pathophysiology of Parkinsonism in WP and PD patients. © 2007 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Chili</li></country></list><tree><country name="Allemagne"><noRegion><name sortKey="Walter, Uwe" sort="Walter, Uwe" uniqKey="Walter U" first="Uwe" last="Walter">Uwe Walter</name></noRegion><name sortKey="Dressler, Dirk" sort="Dressler, Dirk" uniqKey="Dressler D" first="Dirk" last="Dressler">Dirk Dressler</name></country><country name="Chili"><noRegion><name sortKey="Lindemann, Christian" sort="Lindemann, Christian" uniqKey="Lindemann C" first="Christian" last="Lindemann">Christian Lindemann</name></noRegion><name sortKey="Miranda, Marcelo" sort="Miranda, Marcelo" uniqKey="Miranda M" first="Marcelo" last="Miranda">Marcelo Miranda</name><name sortKey="Slachevsky, Andrea" sort="Slachevsky, Andrea" uniqKey="Slachevsky A" first="Andrea" last="Slachevsky">Andrea Slachevsky</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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